HCSGD entry for KLHL4
1. General information
| Official gene symbol | KLHL4 |
|---|---|
| Entrez ID | 56062 |
| Gene full name | kelch-like family member 4 |
| Other gene symbols | DKELCHL KHL4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA ISS | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0772880172 | 0.9259582615 | 0.5867602827 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0696314324 |
| GSE13712_SHEAR | Down | -0.3246482295 |
| GSE13712_STATIC | Down | -0.0374193978 |
| GSE19018 | Up | 0.0743628599 |
| GSE19899_A1 | Up | 0.2236512649 |
| GSE19899_A2 | Up | 0.4340042782 |
| PubMed_21979375_A1 | Up | 0.2799873773 |
| PubMed_21979375_A2 | Up | 0.5317730659 |
| GSE35957 | Up | 0.0811290981 |
| GSE36640 | Up | 0.1366057769 |
| GSE54402 | Up | 0.0663930848 |
| GSE9593 | Up | 0.1602320323 |
| GSE43922 | Up | 1.0710396496 |
| GSE24585 | Up | 0.4015716306 |
| GSE37065 | Down | -0.1608148620 |
| GSE28863_A1 | Down | -0.1047311162 |
| GSE28863_A2 | Down | -0.2164014546 |
| GSE28863_A3 | Up | 0.0708100360 |
| GSE28863_A4 | Up | 0.0762947848 |
| GSE48662 | Down | -0.0081452801 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019091 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
