HCSGD entry for EIF4ENIF1


1. General information

Official gene symbolEIF4ENIF1
Entrez ID56478
Gene full nameeukaryotic translation initiation factor 4E nuclear import factor 1
Other gene symbols4E-T Clast4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003743Translation initiation factor activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEA TAScellular_component
GO:0005737CytoplasmTAScellular_component
GO:0005829CytosolIEAcellular_component
GO:0008565Protein transporter activityTASmolecular_function
GO:0016605PML bodyIEAcellular_component
GO:0016607Nuclear speckIEAcellular_component
GO:0043231Intracellular membrane-bounded organelleIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.55068061240.72602729760.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0805919047
GSE13712_SHEARDown-0.1948576101
GSE13712_STATICDown-0.1378872634
GSE19018Down-0.2333318841
GSE19899_A1Down-0.1536111644
GSE19899_A2Up0.3031449603
PubMed_21979375_A1Up0.4715185681
PubMed_21979375_A2Up0.2690042172
GSE35957Up0.2315798162
GSE36640Up0.4164033866
GSE54402Down-0.1160028263
GSE9593Up0.1994791711
GSE43922Down-0.0520758117
GSE24585Down-0.0265625217
GSE37065Up0.0012902660
GSE28863_A1Down-0.0742732253
GSE28863_A2Up0.0787712315
GSE28863_A3Down-0.3706453688
GSE28863_A4Up0.0770968166
GSE48662Up0.1878339777

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT017657MicroarrayFunctional MTI (Weak)18185580
hsa-miR-93-3pMIMAT0004509MIRT038736CLASHFunctional MTI (Weak)23622248
hsa-miR-652-3pMIMAT0003322MIRT039552CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.