HCSGD entry for AZU1

1. General information

Official gene symbolAZU1
Entrez ID566
Gene full nameazurocidin 1
Other gene symbolsAZAMP AZU CAP37 HBP HUMAZUR NAZC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001774Microglial cell activationIEPbiological_process
GO:0004252Serine-type endopeptidase activityIEAmolecular_function
GO:0005576Extracellular regionNAScellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0006954Inflammatory responseNASbiological_process
GO:0007205Protein kinase C-activating G-protein coupled receptor signaling pathwayTASbiological_process
GO:0008201Heparin bindingNASmolecular_function
GO:0008347Glial cell migrationIDAbiological_process
GO:0015643Toxic substance bindingNASmolecular_function
GO:0042117Monocyte activationTASbiological_process
GO:0042535Positive regulation of tumor necrosis factor biosynthetic processIDAbiological_process
GO:0042582Azurophil granuleIDAcellular_component
GO:0043066Negative regulation of apoptotic processNASbiological_process
GO:0043114Regulation of vascular permeabilityNASbiological_process
GO:0045123Cellular extravasationNASbiological_process
GO:0045348Positive regulation of MHC class II biosynthetic processIEPbiological_process
GO:0045785Positive regulation of cell adhesionIDAbiological_process
GO:0048246Macrophage chemotaxisNASbiological_process
GO:0050725Positive regulation of interleukin-1 beta biosynthetic processIDAbiological_process
GO:0050754Positive regulation of fractalkine biosynthetic processIDAbiological_process
GO:0050766Positive regulation of phagocytosisIDAbiological_process
GO:0050829Defense response to Gram-negative bacteriumTASbiological_process
GO:0050930Induction of positive chemotaxisNASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.47621628360.88755462940.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1463787403
GSE13712_SHEARDown-0.0774655802
GSE13712_STATICDown-0.0167267762
GSE19018Up0.1560482225
GSE19899_A1Up0.0233768542
GSE19899_A2Up0.0427233979
PubMed_21979375_A1Up0.1632284633
PubMed_21979375_A2Down-0.0518450209
GSE35957Down-0.0716085605
GSE36640Down-0.0899214668
GSE54402Down-0.1260690138
GSE9593Up0.0478043390
GSE43922Up0.0611935861
GSE24585Up0.1851278020
GSE37065Down-0.0708249756
GSE28863_A1Down-0.1528191152
GSE28863_A2Down-0.0169682620
GSE28863_A3Up0.4758455352
GSE28863_A4Up0.1806208335
GSE48662Up0.0007227798

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.