HCSGD entry for RAD18
1. General information
| Official gene symbol | RAD18 |
|---|---|
| Entrez ID | 56852 |
| Gene full name | RAD18 homolog (S. cerevisiae) |
| Other gene symbols | RNF73 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000403 | Y-form DNA binding | IDA | molecular_function |
| GO:0000785 | Chromatin | IEA | cellular_component |
| GO:0001741 | XY body | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003684 | Damaged DNA binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA NAS | cellular_component |
| GO:0005657 | Replication fork | IDA | cellular_component |
| GO:0006281 | DNA repair | IEA NAS | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IEA | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0009411 | Response to UV | IEA | biological_process |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0031593 | Polyubiquitin binding | IDA | molecular_function |
| GO:0031625 | Ubiquitin protein ligase binding | IPI | molecular_function |
| GO:0045910 | Negative regulation of DNA recombination | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9795585996 | 0.0146651609 | 0.9999902473 | 0.2384198271 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0944934300 |
| GSE13712_SHEAR | Down | -0.3293568475 |
| GSE13712_STATIC | Up | 0.1145322361 |
| GSE19018 | Up | 0.2824389669 |
| GSE19899_A1 | Up | 0.0327037264 |
| GSE19899_A2 | Down | -0.7467876716 |
| PubMed_21979375_A1 | Down | -0.2325692130 |
| PubMed_21979375_A2 | Down | -0.6880769003 |
| GSE35957 | Down | -0.1175959724 |
| GSE36640 | Down | -1.6856658320 |
| GSE54402 | Down | -0.0578401510 |
| GSE9593 | Down | -0.3504816623 |
| GSE43922 | Down | -0.3630552677 |
| GSE24585 | Down | -0.0950053438 |
| GSE37065 | Up | 0.0319537101 |
| GSE28863_A1 | Down | -0.2799189758 |
| GSE28863_A2 | Down | -0.1040900364 |
| GSE28863_A3 | Down | -0.5843987479 |
| GSE28863_A4 | Down | -0.1058431334 |
| GSE48662 | Down | -0.5109813835 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
