HCSGD entry for SMARCAD1
1. General information
| Official gene symbol | SMARCAD1 |
|---|---|
| Entrez ID | 56916 |
| Gene full name | SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1 |
| Other gene symbols | ADERM ETL1 HEL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000018 | Regulation of DNA recombination | IEP | biological_process |
| GO:0000729 | DNA double-strand break processing | IMP | biological_process |
| GO:0000792 | Heterochromatin | ISS | cellular_component |
| GO:0003676 | Nucleic acid binding | NAS | molecular_function |
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0004386 | Helicase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0006338 | Chromatin remodeling | NAS | biological_process |
| GO:0009117 | Nucleotide metabolic process | NAS | biological_process |
| GO:0016363 | Nuclear matrix | NAS | cellular_component |
| GO:0016568 | Chromatin modification | NAS | biological_process |
| GO:0035861 | Site of double-strand break | IDA | cellular_component |
| GO:0043044 | ATP-dependent chromatin remodeling | IMP | biological_process |
| GO:0043596 | Nuclear replication fork | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0051260 | Protein homooligomerization | NAS | biological_process |
| GO:0051304 | Chromosome separation | IMP | biological_process |
| GO:0070932 | Histone H3 deacetylation | IMP | biological_process |
| GO:0070933 | Histone H4 deacetylation | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9922493446 | 0.0102362144 | 0.9999902473 | 0.2001689450 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1059510824 |
| GSE13712_SHEAR | Down | -0.2961422929 |
| GSE13712_STATIC | Down | -0.2001190544 |
| GSE19018 | Down | -0.1142967352 |
| GSE19899_A1 | Down | -0.5658308585 |
| GSE19899_A2 | Down | -0.5074152637 |
| PubMed_21979375_A1 | Down | -0.6404738444 |
| PubMed_21979375_A2 | Up | 0.1212299689 |
| GSE35957 | Down | -0.3928628879 |
| GSE36640 | Down | -0.7333122539 |
| GSE54402 | Down | -0.1063528877 |
| GSE9593 | Down | -0.2076327632 |
| GSE43922 | Down | -0.0358589326 |
| GSE24585 | Down | -0.0587443792 |
| GSE37065 | Up | 0.2080061420 |
| GSE28863_A1 | Down | -0.0149827649 |
| GSE28863_A2 | Down | -0.1571986528 |
| GSE28863_A3 | Down | -1.0659692760 |
| GSE28863_A4 | Down | -0.2044492229 |
| GSE48662 | Down | -0.6288983678 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-196a-5p | MIMAT0000226 | MIRT026072 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7d-5p | MIMAT0000065 | MIRT032177 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-320a | MIMAT0000510 | MIRT044732 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7a-5p | MIMAT0000062 | MIRT052382 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
