HCSGD entry for CXCR7
1. General information
| Official gene symbol | CXCR7 |
|---|---|
| Entrez ID | 57007 |
| Gene full name | chemokine (C-X-C motif) receptor 7 |
| Other gene symbols | CMKOR1 CXC-R7 CXCR-7 GPR159 RDC-1 RDC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001570 | Vasculogenesis | IEA | biological_process |
| GO:0005044 | Scavenger receptor activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005768 | Endosome | IDA | cellular_component |
| GO:0005769 | Early endosome | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA TAS | cellular_component |
| GO:0005905 | Coated pit | IDA | cellular_component |
| GO:0006935 | Chemotaxis | IEA | biological_process |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0015026 | Coreceptor activity | IEA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016032 | Viral process | IEA | biological_process |
| GO:0016494 | C-X-C chemokine receptor activity | IMP | molecular_function |
| GO:0019958 | C-X-C chemokine binding | IMP | molecular_function |
| GO:0031623 | Receptor internalization | IMP | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0055037 | Recycling endosome | IEA | cellular_component |
| GO:0070098 | Chemokine-mediated signaling pathway | IMP | biological_process |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IMP | biological_process |
| GO:1902230 | Negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0130129364 | 0.4650609361 | 0.2841881426 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1102230927 |
| GSE13712_SHEAR | Down | -1.2639542852 |
| GSE13712_STATIC | Down | -1.2597633608 |
| GSE19018 | Down | -0.1065517377 |
| GSE19899_A1 | Up | 0.1529734089 |
| GSE19899_A2 | Up | 0.4790579482 |
| PubMed_21979375_A1 | Up | 0.5826123519 |
| PubMed_21979375_A2 | Up | 0.3676639628 |
| GSE35957 | Down | -0.8634562997 |
| GSE36640 | Up | 2.1976087907 |
| GSE54402 | Up | 1.6072865234 |
| GSE9593 | Down | -0.2087659621 |
| GSE43922 | Up | 0.0228375559 |
| GSE24585 | Down | -0.1208414423 |
| GSE37065 | Up | 0.3769371178 |
| GSE28863_A1 | Up | 0.6912661761 |
| GSE28863_A2 | Up | 0.4455346965 |
| GSE28863_A3 | Up | 0.1001452390 |
| GSE28863_A4 | Up | 0.0594792672 |
| GSE48662 | Up | 0.9583695994 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019188 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-98-5p | MIMAT0000096 | MIRT027783 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
