HCSGD entry for PARP11


1. General information

Official gene symbolPARP11
Entrez ID57097
Gene full namepoly (ADP-ribose) polymerase family, member 11
Other gene symbolsARTD11 C12orf6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003950NAD+ ADP-ribosyltransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95984204250.11828419130.99999024730.6607296689

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0320749555
GSE13712_SHEARDown-0.3504026839
GSE13712_STATICDown-0.2139118667
GSE19018Down-0.1385408395
GSE19899_A1Up0.0280888657
GSE19899_A2Down-0.4923497272
PubMed_21979375_A1Down-0.2253167384
PubMed_21979375_A2Down-0.0174054200
GSE35957Down-0.0165148246
GSE36640Down-0.5008261019
GSE54402Up0.0167956646
GSE9593Up0.1653682922
GSE43922Down-0.2382865201
GSE24585Up0.1479781666
GSE37065Up0.1699351309
GSE28863_A1Down-0.0103343657
GSE28863_A2Down-0.2753425711
GSE28863_A3Down-0.5369159790
GSE28863_A4Down-0.0123235471
GSE48662Down-0.1485353049

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018797MicroarrayFunctional MTI (Weak)18185580
hsa-miR-122-5pMIMAT0000421MIRT023350MicroarrayFunctional MTI (Weak)17612493
hsa-miR-7-5pMIMAT0000252MIRT025916MicroarrayFunctional MTI (Weak)17612493
hsa-miR-26b-5pMIMAT0000083MIRT050051CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

16077192Moreover, the interaction and cross-talk between p53 and PARP1-1 was discussed
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