HCSGD entry for RALGAPB
1. General information
| Official gene symbol | RALGAPB |
|---|---|
| Entrez ID | 57148 |
| Gene full name | Ral GTPase activating protein, beta subunit (non-catalytic) |
| Other gene symbols | KIAA1219 RalGAPbeta dJ1100H13.1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005096 | GTPase activator activity | IEA | molecular_function |
| GO:0017123 | Ral GTPase activator activity | ISS | molecular_function |
| GO:0032484 | Ral protein signal transduction | IEA | biological_process |
| GO:0032859 | Activation of Ral GTPase activity | ISS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI ISS | molecular_function |
| GO:0051056 | Regulation of small GTPase mediated signal transduction | IEA | biological_process |
| GO:0060178 | Regulation of exocyst localization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0085551461 | 0.9952047757 | 0.2372813488 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1277005119 |
| GSE13712_SHEAR | Up | 0.4340648197 |
| GSE13712_STATIC | Up | 0.0415165413 |
| GSE19018 | Up | 0.3583475570 |
| GSE19899_A1 | Up | 0.1873470874 |
| GSE19899_A2 | Up | 0.8490973345 |
| PubMed_21979375_A1 | Up | 0.6058998164 |
| PubMed_21979375_A2 | Up | 1.7446330767 |
| GSE35957 | Up | 0.2313228131 |
| GSE36640 | Up | 0.5728032473 |
| GSE54402 | Up | 0.1060374314 |
| GSE9593 | Up | 0.3243493884 |
| GSE43922 | Up | 0.2535291202 |
| GSE24585 | Up | 0.1812853674 |
| GSE37065 | Down | -0.0280528055 |
| GSE28863_A1 | Up | 0.6605963757 |
| GSE28863_A2 | Up | 0.3939890006 |
| GSE28863_A3 | Down | -0.2854717670 |
| GSE28863_A4 | Up | 0.0447967787 |
| GSE48662 | Up | 0.1713106644 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7d-5p | MIMAT0000065 | MIRT032129 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-421 | MIMAT0003339 | MIRT039454 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040158 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043719 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-328-3p | MIMAT0000752 | MIRT043758 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT052119 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
