HCSGD entry for SHROOM4

1. General information

Official gene symbolSHROOM4
Entrez ID57477
Gene full nameshroom family member 4
Other gene symbolsSHAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000902Cell morphogenesisIDAbiological_process
GO:0001725Stress fiberISScellular_component
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDA ISScellular_component
GO:0007015Actin filament organizationISSbiological_process
GO:0007420Brain developmentIDAbiological_process
GO:0009898Cytoplasmic side of plasma membraneIDAcellular_component
GO:0009925Basal plasma membraneISScellular_component
GO:0015629Actin cytoskeletonISScellular_component
GO:0016324Apical plasma membraneISScellular_component
GO:0016460Myosin II complexISScellular_component
GO:0030036Actin cytoskeleton organizationNASbiological_process
GO:0030864Cortical actin cytoskeletonISScellular_component
GO:0031941Filamentous actinIDAcellular_component
GO:0050890CognitionIDAbiological_process
GO:0051015Actin filament bindingISSmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78891382170.56195479660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0984290116
GSE13712_SHEARUp0.0146936466
GSE13712_STATICUp0.1284840699
GSE19018Down-0.0373419081
GSE19899_A1Up0.0746861089
GSE19899_A2Up0.0750947239
PubMed_21979375_A1Down-0.5933897641
PubMed_21979375_A2Down-0.1220158678
GSE35957Down-0.1082479106
GSE36640Down-0.1071452420
GSE54402Down-0.0572536665
GSE9593Down-0.0730621112
GSE43922Up0.0359414323
GSE24585Down-0.0520863672
GSE37065Up0.1194911182
GSE28863_A1Down-0.1687825996
GSE28863_A2Up0.3102395092
GSE28863_A3Up0.1208170387
GSE28863_A4Up0.0551382973
GSE48662Up0.0857034949

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018002MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.