HCSGD entry for NLGN4X


1. General information

Official gene symbolNLGN4X
Entrez ID57502
Gene full nameneuroligin 4, X-linked
Other gene symbolsASPGX2 AUTSX2 HLNX HNL4X HNLX NLGN NLGN4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003360Brainstem developmentISSbiological_process
GO:0004872Receptor activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneIDAcellular_component
GO:0007155Cell adhesionIEAbiological_process
GO:0007612LearningIMPbiological_process
GO:0009986Cell surfaceIDAcellular_component
GO:0014069Postsynaptic densityIEAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0021549Cerebellum developmentISSbiological_process
GO:0030054Cell junctionIEAcellular_component
GO:0030182Neuron differentiationNASbiological_process
GO:0030425DendriteIDAcellular_component
GO:0030534Adult behaviorIMPbiological_process
GO:0031404Chloride ion bindingIDAmolecular_function
GO:0035176Social behaviorIMPbiological_process
GO:0035265Organ growthISSbiological_process
GO:0042043Neurexin family protein bindingIDA IPImolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0045202SynapseIBA ISScellular_component
GO:0045211Postsynaptic membraneIEAcellular_component
GO:0045216Cell-cell junction organizationNASbiological_process
GO:0050808Synapse organizationIMP NASbiological_process
GO:0060076Excitatory synapseIDAcellular_component
GO:0071625Vocalization behaviorIMP ISSbiological_process
GO:0090394Negative regulation of excitatory postsynaptic membrane potentialIDAbiological_process
GO:0097105Presynaptic membrane assemblyIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69136887660.42874226660.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1104653126
GSE13712_SHEARUp0.0161258094
GSE13712_STATICUp0.0204117998
GSE19018Up0.0557150396
GSE19899_A1Up0.0718161429
GSE19899_A2Up0.1753468694
PubMed_21979375_A1Down-0.0440148509
PubMed_21979375_A2Down-0.0021674399
GSE35957Up0.0185751708
GSE36640Up0.0480799242
GSE54402Up0.0575062725
GSE9593Down-0.6498396904
GSE43922Up0.0916720958
GSE24585Down-0.1150139596
GSE37065Down-0.3422172002
GSE28863_A1Down-0.1704191311
GSE28863_A2Down-0.3367095646
GSE28863_A3Up0.3341735644
GSE28863_A4Up0.0579643277
GSE48662Up0.0048376503

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-148b-3pMIMAT0000759MIRT019360MicroarrayFunctional MTI (Weak)17612493
hsa-miR-26b-5pMIMAT0000083MIRT029196MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.