HCSGD entry for HCN3
1. General information
| Official gene symbol | HCN3 |
|---|---|
| Entrez ID | 57657 |
| Gene full name | hyperpolarization activated cyclic nucleotide-gated potassium channel 3 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005249 | Voltage-gated potassium channel activity | IBA | molecular_function |
| GO:0005272 | Sodium channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | IBA | cellular_component |
| GO:0007268 | Synaptic transmission | TAS | biological_process |
| GO:0030552 | CAMP binding | IEA | molecular_function |
| GO:0042391 | Regulation of membrane potential | IBA | biological_process |
| GO:0071805 | Potassium ion transmembrane transport | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4244376999 | 0.7389542685 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0733972978 |
| GSE13712_SHEAR | Down | -0.2701043129 |
| GSE13712_STATIC | Up | 0.2078960759 |
| GSE19018 | Down | -0.1126540625 |
| GSE19899_A1 | Up | 0.0477381631 |
| GSE19899_A2 | Down | -0.0695084360 |
| PubMed_21979375_A1 | Down | -0.4695422550 |
| PubMed_21979375_A2 | Up | 0.1335390500 |
| GSE35957 | Up | 0.2127594916 |
| GSE36640 | Up | 0.5284600610 |
| GSE54402 | Down | -0.1844800279 |
| GSE9593 | Down | -0.0268382359 |
| GSE43922 | Up | 0.0527570713 |
| GSE24585 | Up | 0.0835307633 |
| GSE37065 | Up | 0.0641238178 |
| GSE28863_A1 | Up | 0.0457315599 |
| GSE28863_A2 | Up | 0.1670881999 |
| GSE28863_A3 | Up | 0.0844563512 |
| GSE28863_A4 | Down | -0.0673571722 |
| GSE48662 | Up | 0.1094211856 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT026503 | Microarray | Functional MTI (Weak) | 19074876 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
