HCSGD entry for LSM2
1. General information
| Official gene symbol | LSM2 |
|---|---|
| Entrez ID | 57819 |
| Gene full name | LSM2 homolog, U6 small nuclear RNA associated (S. cerevisiae) |
| Other gene symbols | C6orf28 G7B YBL026W snRNP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000288 | Nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay | TAS | biological_process |
| GO:0000398 | MRNA splicing, via spliceosome | IC TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0017070 | U6 snRNA binding | NAS | molecular_function |
| GO:0019901 | Protein kinase binding | IEA | molecular_function |
| GO:0043928 | Exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | TAS | biological_process |
| GO:0071013 | Catalytic step 2 spliceosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9854394438 | 0.0085943125 | 0.9999902473 | 0.1849068627 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0730936070 |
| GSE13712_SHEAR | Down | -0.2252449415 |
| GSE13712_STATIC | Up | 0.0840835946 |
| GSE19018 | Up | 0.0726531235 |
| GSE19899_A1 | Down | -0.5308863549 |
| GSE19899_A2 | Down | -0.9307302704 |
| PubMed_21979375_A1 | Down | -0.3722694409 |
| PubMed_21979375_A2 | Down | -1.4528351696 |
| GSE35957 | Down | -1.6778452548 |
| GSE36640 | Down | -2.0263930634 |
| GSE54402 | Up | 0.0283565792 |
| GSE9593 | Down | -1.0712908313 |
| GSE43922 | Up | 0.0475291323 |
| GSE24585 | Down | -0.3208939126 |
| GSE37065 | Down | -0.2696767815 |
| GSE28863_A1 | Down | -0.0891120976 |
| GSE28863_A2 | Down | -0.0853003199 |
| GSE28863_A3 | Down | -0.0519709839 |
| GSE28863_A4 | Up | 0.0534672568 |
| GSE48662 | Down | -0.2031617015 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-760 | MIMAT0004957 | MIRT036749 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
