HCSGD entry for PEX5

1. General information

Official gene symbolPEX5
Entrez ID5830
Gene full nameperoxisomal biogenesis factor 5
Other gene symbolsPBD2A PBD2B PTS1-BP PTS1R PXR1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000038Very long-chain fatty acid metabolic processIEAbiological_process
GO:0000268Peroxisome targeting sequence bindingIDAmolecular_function
GO:0001764Neuron migrationIEAbiological_process
GO:0005052Peroxisome matrix targeting signal-1 bindingIDA IMP IPImolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIGIcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0005777PeroxisomeIDAcellular_component
GO:0005778Peroxisomal membraneIDAcellular_component
GO:0005782Peroxisomal matrixIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006625Protein targeting to peroxisomeIDA IMPbiological_process
GO:0006635Fatty acid beta-oxidationIEAbiological_process
GO:0007006Mitochondrial membrane organizationIEAbiological_process
GO:0007029Endoplasmic reticulum organizationIEAbiological_process
GO:0007031Peroxisome organizationIEAbiological_process
GO:0008022Protein C-terminus bindingIPImolecular_function
GO:0016020MembraneIDAcellular_component
GO:0016558Protein import into peroxisome matrixIGI IMP NASbiological_process
GO:0016560Protein import into peroxisome matrix, dockingIDAbiological_process
GO:0016561Protein import into peroxisome matrix, translocationIDAbiological_process
GO:0019899Enzyme bindingIPImolecular_function
GO:0021795Cerebral cortex cell migrationIEAbiological_process
GO:0021895Cerebral cortex neuron differentiationIEAbiological_process
GO:0031267Small GTPase bindingIPImolecular_function
GO:0040018Positive regulation of multicellular organism growthIEAbiological_process
GO:0043234Protein complexIDAcellular_component
GO:0045046Protein import into peroxisome membraneIMPbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0048468Cell developmentIEAbiological_process
GO:0050905Neuromuscular processIEAbiological_process
GO:0051262Protein tetramerizationIDAbiological_process
GO:1901094Negative regulation of protein homotetramerizationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11472857030.80147480720.69636453101.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0562309687
GSE13712_SHEARUp0.2099105564
GSE13712_STATICDown-0.0417739687
GSE19018Down-0.1740985388
GSE19899_A1Up0.3746343797
GSE19899_A2Up0.6853615112
PubMed_21979375_A1Up0.4021505589
PubMed_21979375_A2Up0.4503492713
GSE35957Up0.4846492876
GSE36640Up0.0926691045
GSE54402Up0.1158945057
GSE9593Up0.5094831182
GSE43922Up0.3408304652
GSE24585Down-0.4949578717
GSE37065Down-0.2464001750
GSE28863_A1Up0.0124105643
GSE28863_A2Up0.0014527620
GSE28863_A3Down-0.1534096288
GSE28863_A4Down-0.1028508404
GSE48662Up0.0229673491

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-25-3pMIMAT0000081MIRT050249CLASHFunctional MTI (Weak)23622248
hsa-miR-22-3pMIMAT0000077MIRT050469CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.