HCSGD entry for PRUNE
1. General information
| Official gene symbol | PRUNE |
|---|---|
| Entrez ID | 58497 |
| Gene full name | prune exopolyphosphatase |
| Other gene symbols | DRES-17 DRES17 HTCD37 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004427 | Inorganic diphosphatase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0016462 | Pyrophosphatase activity | IEA | molecular_function |
| GO:0030145 | Manganese ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4951326583 | 0.2074252688 | 0.9999902473 | 0.8829456177 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0014268440 |
| GSE13712_SHEAR | Down | -0.3704758698 |
| GSE13712_STATIC | Down | -0.2427402183 |
| GSE19018 | Up | 0.0855226497 |
| GSE19899_A1 | Up | 0.1539642490 |
| GSE19899_A2 | Up | 0.2884188194 |
| PubMed_21979375_A1 | Down | -0.0330239329 |
| PubMed_21979375_A2 | Up | 0.1005773984 |
| GSE35957 | Up | 0.1847497063 |
| GSE36640 | Up | 0.1724886321 |
| GSE54402 | Down | -0.3006881075 |
| GSE9593 | Down | -0.0565696941 |
| GSE43922 | Up | 0.6519553259 |
| GSE24585 | Up | 0.1116022384 |
| GSE37065 | Up | 0.0178747013 |
| GSE28863_A1 | Down | -0.1693564151 |
| GSE28863_A2 | Up | 0.3542905939 |
| GSE28863_A3 | Down | -0.7765256083 |
| GSE28863_A4 | Down | -0.4394451506 |
| GSE48662 | Down | -0.2677368919 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
