HCSGD entry for QDPR
1. General information
| Official gene symbol | QDPR |
|---|---|
| Entrez ID | 5860 |
| Gene full name | quinoid dihydropteridine reductase |
| Other gene symbols | DHPR PKU2 SDR33C1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0004155 | 6,7-dihydropteridine reductase activity | EXP | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006520 | Cellular amino acid metabolic process | TAS | biological_process |
| GO:0006559 | L-phenylalanine catabolic process | TAS | biological_process |
| GO:0006729 | Tetrahydrobiopterin biosynthetic process | IEA | biological_process |
| GO:0009055 | Electron carrier activity | TAS | molecular_function |
| GO:0010044 | Response to aluminum ion | IEA | biological_process |
| GO:0010288 | Response to lead ion | IEA | biological_process |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0033762 | Response to glucagon | IEA | biological_process |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0035690 | Cellular response to drug | IEA | biological_process |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0051066 | Dihydrobiopterin metabolic process | TAS | biological_process |
| GO:0070402 | NADPH binding | IEA | molecular_function |
| GO:0070404 | NADH binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1524302686 | 0.9048285513 | 0.7795059452 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1620876906 |
| GSE13712_SHEAR | Up | 0.2221771225 |
| GSE13712_STATIC | Up | 0.1249370681 |
| GSE19018 | Down | -0.0483425605 |
| GSE19899_A1 | Up | 0.1789088591 |
| GSE19899_A2 | Up | 0.4922592840 |
| PubMed_21979375_A1 | Up | 0.4284583148 |
| PubMed_21979375_A2 | Up | 0.6586642923 |
| GSE35957 | Up | 0.0278130649 |
| GSE36640 | Up | 0.2949342124 |
| GSE54402 | Up | 0.0998903570 |
| GSE9593 | Up | 0.0130833984 |
| GSE43922 | Up | 0.1004864763 |
| GSE24585 | Down | -0.2086937861 |
| GSE37065 | Up | 0.0523427428 |
| GSE28863_A1 | Down | -0.0351758039 |
| GSE28863_A2 | Up | 0.0103126056 |
| GSE28863_A3 | Down | -0.0568372667 |
| GSE28863_A4 | Down | -0.0760371237 |
| GSE48662 | Down | -0.1362480345 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
| 2-(N-Morpholino)-Ethanesulfonic Acid | DB03814 | EXPT02154 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025362 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029076 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
