HCSGD entry for RAD51B


1. General information

Official gene symbolRAD51B
Entrez ID5890
Gene full nameRAD51 homolog B (S. cerevisiae)
Other gene symbolsR51H2 RAD51L1 REC2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusTAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006259DNA metabolic processIEAbiological_process
GO:0006281DNA repairIEAbiological_process
GO:0006310DNA recombinationTASbiological_process
GO:0007131Reciprocal meiotic recombinationTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008094DNA-dependent ATPase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66900744270.77423194030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0622891678
GSE13712_SHEARUp0.1442008702
GSE13712_STATICDown-0.0583355157
GSE19018Up0.2226553485
GSE19899_A1Up0.1090762608
GSE19899_A2Down-0.1556535457
PubMed_21979375_A1Down-0.0254209002
PubMed_21979375_A2Down-0.0357241380
GSE35957Down-0.1330893670
GSE36640Down-0.6471990778
GSE54402Up0.0994197503
GSE9593Up0.0244106844
GSE43922Up0.0077030711
GSE24585Up0.0005212528
GSE37065Up0.2772495604
GSE28863_A1Up0.0947166173
GSE28863_A2Up0.0395753191
GSE28863_A3Down-0.0046228436
GSE28863_A4Up0.0476688595
GSE48662Down-0.0581625447

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041780CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.