HCSGD entry for RFC2


1. General information

Official gene symbolRFC2
Entrez ID5982
Gene full namereplication factor C (activator 1) 2, 40kDa
Other gene symbolsA1 RFC40
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000278Mitotic cell cycleTASbiological_process
GO:0000722Telomere maintenance via recombinationTASbiological_process
GO:0000723Telomere maintenanceTASbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005654NucleoplasmTAScellular_component
GO:0005663DNA replication factor C complexIDAcellular_component
GO:0006260DNA replicationIEA TASbiological_process
GO:0006271DNA strand elongation involved in DNA replicationTASbiological_process
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairTASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006297Nucleotide-excision repair, DNA gap fillingTASbiological_process
GO:0017111Nucleoside-triphosphatase activityIEAmolecular_function
GO:0032201Telomere maintenance via semi-conservative replicationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95805278290.00362227500.99999024730.1224359435

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0993803162
GSE13712_SHEARDown-0.1046702193
GSE13712_STATICDown-0.0725554732
GSE19018Down-0.3779995040
GSE19899_A1Down-0.4235948520
GSE19899_A2Down-1.5411987002
PubMed_21979375_A1Down-0.8960004073
PubMed_21979375_A2Down-2.5768092251
GSE35957Down-1.0857726367
GSE36640Down-2.6895307149
GSE54402Up0.2561010173
GSE9593Down-0.7226463677
GSE43922Down-0.5000900757
GSE24585Up0.1126273177
GSE37065Down-0.1522478754
GSE28863_A1Down-0.1763552260
GSE28863_A2Up0.8137501988
GSE28863_A3Down-0.0655844735
GSE28863_A4Down-0.0526497404
GSE48662Down-0.7435643514

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023820ProteomicsFunctional MTI (Weak)18668040
hsa-miR-149-5pMIMAT0000450MIRT045679CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048154CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.