HCSGD entry for RNASE6
1. General information
| Official gene symbol | RNASE6 |
|---|---|
| Entrez ID | 6039 |
| Gene full name | ribonuclease, RNase A family, k6 |
| Other gene symbols | RNS6 RNasek6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0004540 | Ribonuclease activity | TAS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0006401 | RNA catabolic process | TAS | biological_process |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0016892 | Endoribonuclease activity, producing 3'-phosphomonoesters | IEA | molecular_function |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8873664336 | 0.4288060598 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0216325464 |
| GSE13712_SHEAR | Down | -0.0938128599 |
| GSE13712_STATIC | Down | -0.2931659944 |
| GSE19018 | Up | 0.0987083895 |
| GSE19899_A1 | Up | 0.0658388883 |
| GSE19899_A2 | Up | 0.2471801856 |
| PubMed_21979375_A1 | Up | 0.0045185018 |
| PubMed_21979375_A2 | Up | 0.1484821761 |
| GSE35957 | Down | -0.1936612082 |
| GSE36640 | Down | -0.0846742745 |
| GSE54402 | Up | 0.0670525583 |
| GSE9593 | Down | -0.2605267097 |
| GSE43922 | Up | 0.0106917625 |
| GSE24585 | Up | 0.0298270755 |
| GSE37065 | Down | -0.0059929961 |
| GSE28863_A1 | Up | 0.0878184151 |
| GSE28863_A2 | Down | -0.1613882672 |
| GSE28863_A3 | Up | 0.0469564048 |
| GSE28863_A4 | Down | -0.2238712771 |
| GSE48662 | Down | -0.0508382123 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030200 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
