HCSGD entry for HPSE2
1. General information
| Official gene symbol | HPSE2 |
|---|---|
| Entrez ID | 60495 |
| Gene full name | heparanase 2 |
| Other gene symbols | HPA2 HPR2 UFS UFS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005578 | Proteinaceous extracellular matrix | IDA | cellular_component |
| GO:0005622 | Intracellular | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0030305 | Heparanase activity | IDA TAS | molecular_function |
| GO:0043395 | Heparan sulfate proteoglycan binding | IDA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5819769272 | 0.8533747464 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0593752891 |
| GSE13712_SHEAR | Down | -0.1124417517 |
| GSE13712_STATIC | Down | -0.0340599684 |
| GSE19018 | Down | -0.0823035286 |
| GSE19899_A1 | Up | 0.0343630365 |
| GSE19899_A2 | Down | -0.0362946479 |
| PubMed_21979375_A1 | Up | 0.1764900843 |
| PubMed_21979375_A2 | Down | -0.0619068682 |
| GSE35957 | Up | 0.1807586264 |
| GSE36640 | Up | 0.1486541916 |
| GSE54402 | Up | 0.1493190155 |
| GSE9593 | Down | -0.0106300875 |
| GSE43922 | Up | 0.0147714108 |
| GSE24585 | Up | 0.1805909776 |
| GSE37065 | Down | -0.0027437490 |
| GSE28863_A1 | Down | -0.0857403633 |
| GSE28863_A2 | Down | -0.0931720975 |
| GSE28863_A3 | Up | 0.1304772493 |
| GSE28863_A4 | Up | 0.2231609136 |
| GSE48662 | Down | -0.0019205638 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
