HCSGD entry for RNH1
1. General information
| Official gene symbol | RNH1 |
|---|---|
| Entrez ID | 6050 |
| Gene full name | ribonuclease/angiogenin inhibitor 1 |
| Other gene symbols | RAI RNH |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006402 | MRNA catabolic process | NAS | biological_process |
| GO:0008428 | Ribonuclease inhibitor activity | IDA | molecular_function |
| GO:0032311 | Angiogenin-PRI complex | IPI | cellular_component |
| GO:0043086 | Negative regulation of catalytic activity | IDA | biological_process |
| GO:0045765 | Regulation of angiogenesis | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2513945253 | 0.6298776262 | 0.9412088181 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0134293798 |
| GSE13712_SHEAR | Up | 0.0961174753 |
| GSE13712_STATIC | Up | 0.0162788391 |
| GSE19018 | Up | 0.0192323871 |
| GSE19899_A1 | Down | -0.2398824789 |
| GSE19899_A2 | Down | -0.0569115023 |
| PubMed_21979375_A1 | Up | 0.0196565315 |
| PubMed_21979375_A2 | Down | -0.1113298950 |
| GSE35957 | Up | 0.0004175470 |
| GSE36640 | Down | -0.0409516890 |
| GSE54402 | Down | -0.0220489264 |
| GSE9593 | Up | 0.2297849107 |
| GSE43922 | Down | -0.2095581984 |
| GSE24585 | Up | 0.0247168728 |
| GSE37065 | Down | -0.4433122827 |
| GSE28863_A1 | Down | -0.0138239385 |
| GSE28863_A2 | Up | 0.5488608574 |
| GSE28863_A3 | Up | 0.7097342952 |
| GSE28863_A4 | Up | 0.2219950799 |
| GSE48662 | Up | 0.5882200762 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-125b-5p | MIMAT0000423 | MIRT045994 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049793 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
