HCSGD entry for PROK2

1. General information

Official gene symbolPROK2
Entrez ID60675
Gene full nameprokineticin 2
Other gene symbolsBV8 HH4 KAL4 MIT1 PK2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000187Activation of MAPK activityTASbiological_process
GO:0001525AngiogenesisIDAbiological_process
GO:0001664G-protein coupled receptor bindingTASmolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0006935ChemotaxisIDAbiological_process
GO:0006954Inflammatory responseNASbiological_process
GO:0007186G-protein coupled receptor signaling pathwayNASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationTASbiological_process
GO:0007218Neuropeptide signaling pathwayIEAbiological_process
GO:0007283SpermatogenesisIMPbiological_process
GO:0007623Circadian rhythmIEAbiological_process
GO:0008283Cell proliferationIDAbiological_process
GO:0019233Sensory perception of painTASbiological_process
GO:0043066Negative regulation of apoptotic processIDAbiological_process
GO:0045987Positive regulation of smooth muscle contractionIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80108851110.31973464910.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1955268450
GSE13712_SHEARUp0.1012117805
GSE13712_STATICDown-0.2432291888
GSE19018Up0.0666036099
GSE19899_A1Up0.0173616130
GSE19899_A2Down-0.1043585011
PubMed_21979375_A1Up0.0433840133
PubMed_21979375_A2Down-0.1069785616
GSE35957Down-0.0146564744
GSE36640Up0.0833187921
GSE54402Up0.1945085231
GSE9593Down-0.0155262024
GSE43922Down-0.0152983866
GSE24585Down-0.8055978024
GSE37065Down-0.0082467545
GSE28863_A1Down-0.3406013711
GSE28863_A2Up0.0391035785
GSE28863_A3Up0.2031006162
GSE28863_A4Up0.0177116326
GSE48662Up0.0726876426

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-96-5pMIMAT0000095MIRT027934SequencingFunctional MTI (Weak)20371350
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.