HCSGD entry for RPL10

1. General information

Official gene symbolRPL10
Entrez ID6134
Gene full nameribosomal protein L10
Other gene symbolsAUTSX5 DXS648 DXS648E L10 NOV QM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0003735Structural constituent of ribosomeIDA IEA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006412TranslationIC IEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022625Cytosolic large ribosomal subunitIDAcellular_component
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96285333380.64688058960.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.1949494979
GSE28863_A2Down-0.0447745585
GSE28863_A3Down-0.1382784018
GSE28863_A4Up0.0693402010
GSE48662Up0.0473849581

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-16-5pMIMAT0000069MIRT031375ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031375CLASHFunctional MTI (Weak)23622248
hsa-miR-744-5pMIMAT0004945MIRT037586CLASHFunctional MTI (Weak)23622248
hsa-miR-505-5pMIMAT0004776MIRT037945CLASHFunctional MTI (Weak)23622248
hsa-miR-423-5pMIMAT0004748MIRT038172CLASHFunctional MTI (Weak)23622248
hsa-miR-22-5pMIMAT0004495MIRT038962CLASHFunctional MTI (Weak)23622248
hsa-miR-504-5pMIMAT0002875MIRT041089CLASHFunctional MTI (Weak)23622248
hsa-miR-324-3pMIMAT0000762MIRT042981CLASHFunctional MTI (Weak)23622248
hsa-miR-195-5pMIMAT0000461MIRT044868CLASHFunctional MTI (Weak)23622248
hsa-miR-100-5pMIMAT0000098MIRT048579CLASHFunctional MTI (Weak)23622248
hsa-let-7e-5pMIMAT0000066MIRT051433CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

25785348This includes several translation initiation factors (eIF2C2, eIF2B4, eIF3I, eIF3L, eIF4A1) and elongation factors (eEF1G, eEF1A) as well as 40S (RPS4X, RPS7, RPS11 and RPS20) and 60S ribosomal subunits (RPL10, RPL11, RPL18 and RPL35a)
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