HCSGD entry for S100A4
1. General information
| Official gene symbol | S100A4 |
|---|---|
| Entrez ID | 6275 |
| Gene full name | S100 calcium binding protein A4 |
| Other gene symbols | 18A2 42A CAPL FSP1 MTS1 P9KA PEL98 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001837 | Epithelial to mesenchymal transition | TAS | biological_process |
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IEA | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043123 | Positive regulation of I-kappaB kinase/NF-kappaB signaling | IDA | biological_process |
| GO:0048306 | Calcium-dependent protein binding | IEA | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0050786 | RAGE receptor binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2639915809 | 0.0046613237 | 0.9585490964 | 0.1383209696 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2061320168 |
| GSE13712_SHEAR | Down | -0.9422572968 |
| GSE13712_STATIC | Down | -0.2915879128 |
| GSE19018 | Up | 0.4603556100 |
| GSE19899_A1 | Down | -0.4438797020 |
| GSE19899_A2 | Down | -2.4703577670 |
| PubMed_21979375_A1 | Down | -0.9802841904 |
| PubMed_21979375_A2 | Down | -1.3098200598 |
| GSE35957 | Up | 0.1986308478 |
| GSE36640 | Down | -0.1546232201 |
| GSE54402 | Down | -0.8855953107 |
| GSE9593 | Up | 0.9195030717 |
| GSE43922 | Down | -0.1285179512 |
| GSE24585 | Down | -0.2760526007 |
| GSE37065 | Up | 0.1611037330 |
| GSE28863_A1 | Down | -0.2301419901 |
| GSE28863_A2 | Down | -0.2143851613 |
| GSE28863_A3 | Up | 0.2817808736 |
| GSE28863_A4 | Up | 0.2780069696 |
| GSE48662 | Down | -0.0305849460 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 23969227 | Stringent reduction of the extensive proteomic data from this tumor cell model revealed a list of 59 markers including proteins identified in our former studies and a number of novel proteins involved in tumorigenesis and metastasis such as SFN, S100A4, ANXA2, and LGALS1 |
| 21622994 | Interestingly, the expression of fibroblast-specific protein-1 was higher in uremic MSCs |
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