HCSGD entry for SAA1

1. General information

Official gene symbolSAA1
Entrez ID6288
Gene full nameserum amyloid A1
Other gene symbolsPIG4 SAA SAA2 TP53I4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001664G-protein coupled receptor bindingIDAmolecular_function
GO:0005576Extracellular regionNAS TAScellular_component
GO:0006953Acute-phase responseIEA NASbiological_process
GO:0007204Positive regulation of cytosolic calcium ion concentrationIDA NASbiological_process
GO:0030168Platelet activationNASbiological_process
GO:0030593Neutrophil chemotaxisNASbiological_process
GO:0034364High-density lipoprotein particleIEAcellular_component
GO:0045087Innate immune responseTASbiological_process
GO:0045785Positive regulation of cell adhesionIDA NASbiological_process
GO:0048246Macrophage chemotaxisIDAbiological_process
GO:0048247Lymphocyte chemotaxisIDAbiological_process
GO:0050708Regulation of protein secretionNASbiological_process
GO:0050715Positive regulation of cytokine secretionIDAbiological_process
GO:0050716Positive regulation of interleukin-1 secretionNASbiological_process
GO:0050728Negative regulation of inflammatory responseNASbiological_process
GO:0071682Endocytic vesicle lumenTAScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.30931572130.94069881080.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.2739724269
GSE24585Down-0.1368115939
GSE37065Down-0.0515772632
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up1.2563738812

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

Human Serum AlbuminDB00062 BTD00059 | BIOD00059
Serum albumin iodonatedDB00064 BTD00089 | BIOD00089

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025456ProteomicsFunctional MTI (Weak)21566225
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.