HCSGD entry for MSMO1
1. General information
| Official gene symbol | MSMO1 |
|---|---|
| Entrez ID | 6307 |
| Gene full name | methylsterol monooxygenase 1 |
| Other gene symbols | DESP4 ERG25 SC4MOL |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000254 | C-4 methylsterol oxidase activity | IEA | molecular_function |
| GO:0005506 | Iron ion binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0006631 | Fatty acid metabolic process | TAS | biological_process |
| GO:0006633 | Fatty acid biosynthetic process | IEA | biological_process |
| GO:0006695 | Cholesterol biosynthetic process | TAS | biological_process |
| GO:0008202 | Steroid metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016491 | Oxidoreductase activity | IEA | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0188879146 | 0.1088875233 | 0.3361384719 | 0.6310524218 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8865581492 |
| GSE13712_SHEAR | Down | -0.3825869450 |
| GSE13712_STATIC | Down | -0.3600511920 |
| GSE19018 | Down | -0.1603532329 |
| GSE19899_A1 | Up | 1.3666499798 |
| GSE19899_A2 | Up | 1.5489804041 |
| PubMed_21979375_A1 | Down | -0.6708800476 |
| PubMed_21979375_A2 | Up | 0.8317807267 |
| GSE35957 | Up | 0.1783009294 |
| GSE36640 | Up | 1.6337388531 |
| GSE54402 | Down | -0.1228203316 |
| GSE9593 | Up | 0.1347696031 |
| GSE43922 | Up | 0.4903410149 |
| GSE24585 | Down | -0.6583438768 |
| GSE37065 | Up | 0.3875208884 |
| GSE28863_A1 | Down | -0.3167667567 |
| GSE28863_A2 | Up | 0.2710755983 |
| GSE28863_A3 | Down | -0.8508609770 |
| GSE28863_A4 | Down | -0.1880060987 |
| GSE48662 | Down | -0.3673227832 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| NADH | DB00157 | NUTR00041 | DB01907 | EXPT02287 | DB03527 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19a-3p | MIMAT0000073 | MIRT007120 | Luciferase reporter assay | Functional MTI | 23451058 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018951 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030172 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051607 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
