HCSGD entry for SCN1A
1. General information
| Official gene symbol | SCN1A |
|---|---|
| Entrez ID | 6323 |
| Gene full name | sodium channel, voltage-gated, type I, alpha subunit |
| Other gene symbols | EIEE6 FEB3 FEB3A FHM3 GEFSP2 HBSCI NAC1 Nav1.1 SCN1 SMEI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001518 | Voltage-gated sodium channel complex | IEA | cellular_component |
| GO:0005248 | Voltage-gated sodium channel activity | NAS | molecular_function |
| GO:0006814 | Sodium ion transport | NAS | biological_process |
| GO:0007628 | Adult walking behavior | IEA | biological_process |
| GO:0014704 | Intercalated disc | IEA | cellular_component |
| GO:0019227 | Neuronal action potential propagation | IEA | biological_process |
| GO:0019228 | Neuronal action potential | IEA | biological_process |
| GO:0030018 | Z disc | ISS | cellular_component |
| GO:0030315 | T-tubule | IEA | cellular_component |
| GO:0033268 | Node of Ranvier | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | NAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | NAS | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043194 | Axon initial segment | IEA | cellular_component |
| GO:0050884 | Neuromuscular process controlling posture | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0692149272 | 0.9287224991 | 0.5628659870 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1349335679 |
| GSE13712_SHEAR | Down | -0.0572994756 |
| GSE13712_STATIC | Up | 0.1184825204 |
| GSE19018 | Up | 0.0350793890 |
| GSE19899_A1 | Down | -0.0448158016 |
| GSE19899_A2 | Down | -0.0619743308 |
| PubMed_21979375_A1 | Down | -0.2889697412 |
| PubMed_21979375_A2 | Down | -0.0999652697 |
| GSE35957 | Up | 0.4994898106 |
| GSE36640 | Up | 0.1676419574 |
| GSE54402 | Up | 0.0941739278 |
| GSE9593 | Up | 0.3491691721 |
| GSE43922 | Up | 0.0118004408 |
| GSE24585 | Up | 0.1753313576 |
| GSE37065 | Down | -0.0253173382 |
| GSE28863_A1 | Up | 0.0301140519 |
| GSE28863_A2 | Up | 3.1662975158 |
| GSE28863_A3 | Up | 0.1152023952 |
| GSE28863_A4 | Down | -0.0469126392 |
| GSE48662 | Up | 0.0461510821 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Phenytoin | DB00252 | APRD00241 |
| Topiramate | DB00273 | APRD00237 |
| Zonisamide | DB00909 | APRD00004 |
| Phenacemide | DB01121 | APRD00089 |
| Phenazopyridine | DB01438 | - |
| Dronedarone | DB04855 | - |
| Permethrin | DB04930 | - |
| Tetrodotoxin | DB05232 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-3p | MIMAT0004509 | MIRT038738 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
