HCSGD entry for SCN4A

1. General information

Official gene symbolSCN4A
Entrez ID6329
Gene full namesodium channel, voltage-gated, type IV, alpha subunit
Other gene symbolsHOKPP2 HYKPP HYPP NAC1A Na(V)1.4 Nav1.4 SkM1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001518Voltage-gated sodium channel complexIEAcellular_component
GO:0005248Voltage-gated sodium channel activityIEAmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006814Sodium ion transportTASbiological_process
GO:0006936Muscle contractionTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.58393160590.77349805480.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0808830164
GSE13712_SHEARDown-0.1584710197
GSE13712_STATICDown-0.0215736312
GSE19018Up0.0376693108
GSE19899_A1Up0.1144183276
GSE19899_A2Up0.3677441391
PubMed_21979375_A1Down-0.2755396259
PubMed_21979375_A2Down-0.2325190768
GSE35957Up0.2570767095
GSE36640Down-0.0247902141
GSE54402Down-0.1065064197
GSE9593Up0.2068563668
GSE43922Up0.0510802758
GSE24585Up0.0137458683
GSE37065Down-0.0659624537
GSE28863_A1Down-0.1050997581
GSE28863_A2Up0.0842325997
GSE28863_A3Up0.3404751774
GSE28863_A4Up0.1313666807
GSE48662Down-0.0147745544

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

DiclofenacDB00586 APRD00527
PropofolDB00818 APRD01201 | EXPT02558 | DB05893
ZonisamideDB00909 APRD00004
FlecainideDB01195 APRD00129

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018528MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.