HCSGD entry for BID

1. General information

Official gene symbolBID
Entrez ID637
Gene full nameBH3 interacting domain death agonist
Other gene symbolsFP497
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001836Release of cytochrome c from mitochondriaIDAbiological_process
GO:0005123Death receptor bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionTAScellular_component
GO:0005741Mitochondrial outer membraneTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006626Protein targeting to mitochondrionIEAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006919Activation of cysteine-type endopeptidase activity involved in apoptotic processIEAbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0008625Extrinsic apoptotic signaling pathway via death domain receptorsTASbiological_process
GO:0008637Apoptotic mitochondrial changesTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0031625Ubiquitin protein ligase bindingIEAmolecular_function
GO:0032355Response to estradiolIEAbiological_process
GO:0032461Positive regulation of protein oligomerizationIDAbiological_process
GO:0032464Positive regulation of protein homooligomerizationIDAbiological_process
GO:0032592Integral component of mitochondrial membraneIEAcellular_component
GO:0034349Glial cell apoptotic processIEAbiological_process
GO:0042127Regulation of cell proliferationIEAbiological_process
GO:0042770Signal transduction in response to DNA damageTASbiological_process
GO:0043065Positive regulation of apoptotic processIMPbiological_process
GO:0051260Protein homooligomerizationIEAbiological_process
GO:0051402Neuron apoptotic processTASbiological_process
GO:0090150Establishment of protein localization to membraneIDAbiological_process
GO:0090200Positive regulation of release of cytochrome c from mitochondriaIGI IMPbiological_process
GO:0097193Intrinsic apoptotic signaling pathwayTASbiological_process
GO:1900740Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathwayTASbiological_process
GO:1901030Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathwayTASbiological_process
GO:1902108Regulation of mitochondrial membrane permeability involved in apoptotic processIEAbiological_process
GO:2000045Regulation of G1/S transition of mitotic cell cycleIEAbiological_process
GO:2001238Positive regulation of extrinsic apoptotic signaling pathwayIMPbiological_process
GO:2001244Positive regulation of intrinsic apoptotic signaling pathwayTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01083697430.99464921550.26362348071.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3107901741
GSE13712_SHEARUp0.1282872842
GSE13712_STATICUp0.2086777724
GSE19018Down-0.0974108438
GSE19899_A1Up0.5240743378
GSE19899_A2Up0.8838444679
PubMed_21979375_A1Up1.0238340974
PubMed_21979375_A2Up0.5163959347
GSE35957Down-0.1290835242
GSE36640Up0.8717392696
GSE54402Up0.3517765742
GSE9593Up0.9220823977
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Down-0.1334963630

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-149-5pMIMAT0000450MIRT045661CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049655CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.