HCSGD entry for PKNOX2
1. General information
| Official gene symbol | PKNOX2 |
|---|---|
| Entrez ID | 63876 |
| Gene full name | PBX/knotted 1 homeobox 2 |
| Other gene symbols | PREP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0003785 | Actin monomer binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0015629 | Actin cytoskeleton | IEA | cellular_component |
| GO:0015630 | Microtubule cytoskeleton | IEA | cellular_component |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0051015 | Actin filament binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9277917746 | 0.0820142016 | 0.9999902473 | 0.5429283061 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0620847836 |
| GSE13712_SHEAR | Down | -0.2939481484 |
| GSE13712_STATIC | Down | -0.0728886455 |
| GSE19018 | Up | 0.0610654053 |
| GSE19899_A1 | Down | -0.0067995793 |
| GSE19899_A2 | Down | -0.1807365514 |
| PubMed_21979375_A1 | Down | -0.2703952618 |
| PubMed_21979375_A2 | Down | -0.2801629199 |
| GSE35957 | Up | 0.3291655657 |
| GSE36640 | Down | -1.1891428179 |
| GSE54402 | Down | -0.4376998177 |
| GSE9593 | Down | -0.1316931592 |
| GSE43922 | Up | 0.0325360165 |
| GSE24585 | Up | 0.0655281543 |
| GSE37065 | Down | -0.0730329524 |
| GSE28863_A1 | Down | -0.2442897311 |
| GSE28863_A2 | Down | -0.1653729655 |
| GSE28863_A3 | Up | 0.1700974523 |
| GSE28863_A4 | Up | 0.1075926690 |
| GSE48662 | Down | -0.1333646045 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
