HCSGD entry for ZNF335

1. General information

Official gene symbolZNF335
Entrez ID63925
Gene full namezinc finger protein 335
Other gene symbolsMCPH10 NIF-1 NIF1 NIF2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000979RNA polymerase II core promoter sequence-specific DNA bindingIEAmolecular_function
GO:0001701In utero embryonic developmentIEAbiological_process
GO:0002052Positive regulation of neuroblast proliferationISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusISScellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0007420Brain developmentIMPbiological_process
GO:0021895Cerebral cortex neuron differentiationIEAbiological_process
GO:0035097Histone methyltransferase complexIDAcellular_component
GO:0040029Regulation of gene expression, epigeneticIMPbiological_process
GO:0044212Transcription regulatory region DNA bindingISSmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:0048812Neuron projection morphogenesisISSbiological_process
GO:0048854Brain morphogenesisIEAbiological_process
GO:0050671Positive regulation of lymphocyte proliferationIMPbiological_process
GO:0050769Positive regulation of neurogenesisIMPbiological_process
GO:0051569Regulation of histone H3-K4 methylationIEAbiological_process
GO:0080182Histone H3-K4 trimethylationIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82895826150.47406971240.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0531821818
GSE13712_SHEARDown-0.0767841353
GSE13712_STATICDown-0.1268682923
GSE19018Up0.1331604551
GSE19899_A1Down-0.0542735061
GSE19899_A2Up0.1154253826
PubMed_21979375_A1Up0.3886038940
PubMed_21979375_A2Up0.2756502013
GSE35957Down-0.1913703353
GSE36640Up0.0001391176
GSE54402Up0.1162018719
GSE9593Down-0.0350158538
GSE43922Up0.1575328868
GSE24585Down-0.0516344992
GSE37065Down-0.0952151827
GSE28863_A1Down-0.2005999405
GSE28863_A2Down-0.3682509378
GSE28863_A3Up0.1898229522
GSE28863_A4Down-0.2651593337
GSE48662Up0.0291564723

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.