HCSGD entry for MCCC2


1. General information

Official gene symbolMCCC2
Entrez ID64087
Gene full namemethylcrotonoyl-CoA carboxylase 2 (beta)
Other gene symbolsMCCB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004485Methylcrotonoyl-CoA carboxylase activityIDA NASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005739MitochondrionNAScellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0006552Leucine catabolic processIEA TASbiological_process
GO:0006766Vitamin metabolic processTASbiological_process
GO:0006767Water-soluble vitamin metabolic processTASbiological_process
GO:0006768Biotin metabolic processTASbiological_process
GO:0009083Branched-chain amino acid catabolic processTASbiological_process
GO:0015936Coenzyme A metabolic processIEAbiological_process
GO:0016874Ligase activityIEAmolecular_function
GO:0034641Cellular nitrogen compound metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97430497320.03811477530.99999024730.3679023836

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1795866513
GSE13712_SHEARDown-0.1075414716
GSE13712_STATICUp0.0131010633
GSE19018Down-0.6595314941
GSE19899_A1Down-0.3780999124
GSE19899_A2Down-0.2035719012
PubMed_21979375_A1Down-0.2125649743
PubMed_21979375_A2Down-0.1037155594
GSE35957Down-0.0756800997
GSE36640Down-0.7778300637
GSE54402Up0.0050822999
GSE9593Down-0.0964072477
GSE43922Down-0.4943606482
GSE24585Down-0.1599564585
GSE37065Down-0.0317059238
GSE28863_A1Up0.2379947369
GSE28863_A2Up0.1384658556
GSE28863_A3Down-0.3283596190
GSE28863_A4Down-0.2110633240
GSE48662Down-0.5724129359

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-193b-3pMIMAT0002819MIRT016273ProteomicsFunctional MTI (Weak)21512034
hsa-miR-769-5pMIMAT0003886MIRT039205CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.