HCSGD entry for HIF3A

1. General information

Official gene symbolHIF3A
Entrez ID64344
Gene full namehypoxia inducible factor 3, alpha subunit
Other gene symbolsHIF-3A IPAS MOP7 PASD7 bHLHe17
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001666Response to hypoxiaIEAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0003713Transcription coactivator activityIDAmolecular_function
GO:0003714Transcription corepressor activityIDAmolecular_function
GO:0004871Signal transducer activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIEAbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0061418Regulation of transcription from RNA polymerase II promoter in response to hypoxiaTASbiological_process
GO:0071456Cellular response to hypoxiaIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53584530600.56616051440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0783289559
GSE13712_SHEARDown-0.9757277331
GSE13712_STATICDown-0.1647930771
GSE19018Up0.0333171585
GSE19899_A1Up0.0176423402
GSE19899_A2Up0.0223025271
PubMed_21979375_A1Up0.0679808455
PubMed_21979375_A2Up0.0076321278
GSE35957Up0.0731173791
GSE36640Up0.0092136557
GSE54402Up0.5832008026
GSE9593Up0.0079250920
GSE43922Up0.0622055120
GSE24585Down-0.2717100759
GSE37065Down-0.1338860331
GSE28863_A1Up0.0192559568
GSE28863_A2Down-0.1052450924
GSE28863_A3Up0.3753907709
GSE28863_A4Up0.0128252921
GSE48662Up0.5477963121

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023941MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.