HCSGD entry for SUDS3
1. General information
| Official gene symbol | SUDS3 |
|---|---|
| Entrez ID | 64426 |
| Gene full name | suppressor of defective silencing 3 homolog (S. cerevisiae) |
| Other gene symbols | SAP45 SDS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0004407 | Histone deacetylase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016575 | Histone deacetylation | IDA | biological_process |
| GO:0016580 | Sin3 complex | ISS | cellular_component |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0042826 | Histone deacetylase binding | ISS | molecular_function |
| GO:0043065 | Positive regulation of apoptotic process | IMP | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7638447323 | 0.0733113673 | 0.9999902473 | 0.5102302694 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4120079478 |
| GSE13712_SHEAR | Down | -0.0542666336 |
| GSE13712_STATIC | Down | -0.1180966688 |
| GSE19018 | Up | 0.0219120330 |
| GSE19899_A1 | Down | -0.2043910604 |
| GSE19899_A2 | Down | -0.9488447091 |
| PubMed_21979375_A1 | Down | -0.8430369312 |
| PubMed_21979375_A2 | Down | -0.6947439574 |
| GSE35957 | Down | -0.2101827086 |
| GSE36640 | Down | -0.1452410020 |
| GSE54402 | Up | 0.1610748922 |
| GSE9593 | Down | -0.2548586548 |
| GSE43922 | Down | -0.0580718093 |
| GSE24585 | Up | 0.0942371059 |
| GSE37065 | Down | -0.0483751789 |
| GSE28863_A1 | Up | 0.2295520060 |
| GSE28863_A2 | Up | 0.3571700801 |
| GSE28863_A3 | Down | -0.0286972358 |
| GSE28863_A4 | Up | 0.2714879920 |
| GSE48662 | Up | 0.1101013369 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT048097 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-99a-5p | MIMAT0000097 | MIRT048697 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
