HCSGD entry for SH3BGRL
1. General information
| Official gene symbol | SH3BGRL |
|---|---|
| Entrez ID | 6451 |
| Gene full name | SH3 domain binding glutamic acid-rich protein like |
| Other gene symbols | SH3BGR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9130480111 | 0.0223777364 | 0.9999902473 | 0.2874594436 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2741330715 |
| GSE13712_SHEAR | Down | -0.5251009017 |
| GSE13712_STATIC | Down | -0.2572144184 |
| GSE19018 | Up | 0.1763476354 |
| GSE19899_A1 | Down | -0.6952134634 |
| GSE19899_A2 | Down | -0.7924194609 |
| PubMed_21979375_A1 | Down | -1.0640504486 |
| PubMed_21979375_A2 | Down | -1.2232289935 |
| GSE35957 | Up | 0.1878123810 |
| GSE36640 | Up | 0.4039433963 |
| GSE54402 | Down | -0.5298076266 |
| GSE9593 | Up | 0.4712005954 |
| GSE43922 | Down | -0.6279559224 |
| GSE24585 | Up | 0.2919462166 |
| GSE37065 | Up | 0.1165198441 |
| GSE28863_A1 | Down | -0.0148478887 |
| GSE28863_A2 | Down | -0.0575082087 |
| GSE28863_A3 | Down | -0.0397675356 |
| GSE28863_A4 | Up | 0.0964018347 |
| GSE48662 | Down | -0.3501103660 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021777 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT022023 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025132 | Microarray | Functional MTI (Weak) | 17612493 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
