HCSGD entry for CLEC7A

1. General information

Official gene symbolCLEC7A
Entrez ID64581
Gene full nameC-type lectin domain family 7, member A
Other gene symbolsBGR CANDF4 CLECSF12 DECTIN1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001846Opsonin bindingIEAmolecular_function
GO:0001872(1->3)-beta-D-glucan bindingIEAmolecular_function
GO:0001874(1->3)-beta-D-glucan receptor activityIEAmolecular_function
GO:0001879Detection of yeastIEAbiological_process
GO:0002366Leukocyte activation involved in immune responseIEAbiological_process
GO:0002752Cell surface pattern recognition receptor signaling pathwayIEAbiological_process
GO:0005737CytoplasmIEAcellular_component
GO:0006910Phagocytosis, recognitionIDAbiological_process
GO:0006911Phagocytosis, engulfmentIEAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0008037Cell recognitionIDAbiological_process
GO:0008329Signaling pattern recognition receptor activityIDAmolecular_function
GO:0009756Carbohydrate mediated signalingTASbiological_process
GO:0009897External side of plasma membraneIEAcellular_component
GO:0016021Integral component of membraneTAScellular_component
GO:0016337Cell-cell adhesionIEAbiological_process
GO:0030246Carbohydrate bindingIDAmolecular_function
GO:0032760Positive regulation of tumor necrosis factor productionIEAbiological_process
GO:0042110T cell activationTASbiological_process
GO:0042287MHC protein bindingNASmolecular_function
GO:0042832Defense response to protozoanNASbiological_process
GO:0045087Innate immune responseIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050766Positive regulation of phagocytosisIEAbiological_process
GO:0071226Cellular response to molecule of fungal originIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83747125490.85937066220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1086092033
GSE13712_SHEARDown-0.0509846648
GSE13712_STATICDown-0.1190762105
GSE19018Up0.0466927552
GSE19899_A1Up0.0907656738
GSE19899_A2Up0.0231036004
PubMed_21979375_A1Up0.0329608377
PubMed_21979375_A2Up0.0551457822
GSE35957Up0.0655111547
GSE36640Up0.1022635483
GSE54402Up0.0131986668
GSE9593Down-0.0133216024
GSE43922Up0.0222188060
GSE24585Down-0.1612758552
GSE37065Down-0.0079106649
GSE28863_A1Up0.0180986983
GSE28863_A2Down-0.0578073121
GSE28863_A3Up0.1246112050
GSE28863_A4Down-0.0572954917
GSE48662Up0.0383083528

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.