HCSGD entry for ELOVL1
1. General information
| Official gene symbol | ELOVL1 |
|---|---|
| Entrez ID | 64834 |
| Gene full name | ELOVL fatty acid elongase 1 |
| Other gene symbols | Ssc1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0009922 | Fatty acid elongase activity | IDA | molecular_function |
| GO:0019367 | Fatty acid elongation, saturated fatty acid | IDA | biological_process |
| GO:0019432 | Triglyceride biosynthetic process | TAS | biological_process |
| GO:0030148 | Sphingolipid biosynthetic process | IMP | biological_process |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | NAS | cellular_component |
| GO:0034625 | Fatty acid elongation, monounsaturated fatty acid | IDA | biological_process |
| GO:0035338 | Long-chain fatty-acyl-CoA biosynthetic process | TAS | biological_process |
| GO:0042761 | Very long-chain fatty acid biosynthetic process | IDA | biological_process |
| GO:0044255 | Cellular lipid metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9605045781 | 0.3976207857 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | - | - |
| GSE13712_SHEAR | - | - |
| GSE13712_STATIC | - | - |
| GSE19018 | - | - |
| GSE19899_A1 | - | - |
| GSE19899_A2 | - | - |
| PubMed_21979375_A1 | - | - |
| PubMed_21979375_A2 | - | - |
| GSE35957 | - | - |
| GSE36640 | - | - |
| GSE54402 | - | - |
| GSE9593 | - | - |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Down | -0.5361326435 |
| GSE28863_A2 | Up | 0.0215134305 |
| GSE28863_A3 | Down | -0.1374753817 |
| GSE28863_A4 | Down | -0.0912625649 |
| GSE48662 | Up | 0.3790985073 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002696 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002696 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024485 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026598 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031693 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032337 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-455-3p | MIMAT0004784 | MIRT037904 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-652-3p | MIMAT0003322 | MIRT039565 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042165 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
