HCSGD entry for SLC2A2
1. General information
| Official gene symbol | SLC2A2 |
|---|---|
| Entrez ID | 6514 |
| Gene full name | solute carrier family 2 (facilitated glucose transporter), member 2 |
| Other gene symbols | GLUT2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005355 | Glucose transmembrane transporter activity | EXP | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0005903 | Brush border | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006112 | Energy reserve metabolic process | TAS | biological_process |
| GO:0008645 | Hexose transport | TAS | biological_process |
| GO:0015149 | Hexose transmembrane transporter activity | TAS | molecular_function |
| GO:0015758 | Glucose transport | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0022891 | Substrate-specific transmembrane transporter activity | IEA | molecular_function |
| GO:0031018 | Endocrine pancreas development | TAS | biological_process |
| GO:0033300 | Dehydroascorbic acid transporter activity | IEA | molecular_function |
| GO:0034219 | Carbohydrate transmembrane transport | EXP TAS | biological_process |
| GO:0035428 | Hexose transmembrane transport | EXP TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0050796 | Regulation of insulin secretion | TAS | biological_process |
| GO:0055056 | D-glucose transmembrane transporter activity | IEA | molecular_function |
| GO:0055085 | Transmembrane transport | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6424887048 | 0.8067321796 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0227546422 |
| GSE13712_SHEAR | Down | -0.0511774224 |
| GSE13712_STATIC | Down | -0.0054649897 |
| GSE19018 | Down | -0.1427684605 |
| GSE19899_A1 | Up | 0.1391111638 |
| GSE19899_A2 | Down | -0.0175385829 |
| PubMed_21979375_A1 | Down | -0.1060045186 |
| PubMed_21979375_A2 | Down | -0.0490024586 |
| GSE35957 | Up | 0.1807730182 |
| GSE36640 | Down | -0.0933979822 |
| GSE54402 | Up | 0.0545828212 |
| GSE9593 | Down | -0.1052234549 |
| GSE43922 | Up | 0.1582832593 |
| GSE24585 | Up | 0.1149180608 |
| GSE37065 | Down | -0.0038299248 |
| GSE28863_A1 | Up | 0.0140801632 |
| GSE28863_A2 | Up | 0.0755858485 |
| GSE28863_A3 | Up | 0.1937072812 |
| GSE28863_A4 | Up | 0.1152621034 |
| GSE48662 | Up | 0.0068283857 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25263463 | GLUT2 and GLUT4 expressions were studied in HepG2 cells and human liver tissue |
| 25263463 | Further, GLUT2 and GLUT4 expressions were studied in three independent chronic liver disease cohorts |
| 25263463 | Increased GLUT4 and decreased GLUT2 expressions were evident in senescent cells, human cirrhotic liver tissue and publically available liver disease datasets |
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