HCSGD entry for MPPE1
1. General information
| Official gene symbol | MPPE1 |
|---|---|
| Entrez ID | 65258 |
| Gene full name | metallophosphoesterase 1 |
| Other gene symbols | PGAP5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | ISS | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005801 | Cis-Golgi network | ISS | cellular_component |
| GO:0006506 | GPI anchor biosynthetic process | ISS | biological_process |
| GO:0006888 | ER to Golgi vesicle-mediated transport | ISS | biological_process |
| GO:0008081 | Phosphoric diester hydrolase activity | ISS | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016787 | Hydrolase activity | IEA | molecular_function |
| GO:0030145 | Manganese ion binding | ISS | molecular_function |
| GO:0033116 | Endoplasmic reticulum-Golgi intermediate compartment membrane | IEA | cellular_component |
| GO:0034235 | GPI anchor binding | ISS | molecular_function |
| GO:0070971 | Endoplasmic reticulum exit site | ISS | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7151927700 | 0.0284306333 | 0.9999902473 | 0.3205947323 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0903884942 |
| GSE13712_SHEAR | Down | -0.4187774344 |
| GSE13712_STATIC | Down | -0.1928405763 |
| GSE19018 | Down | -0.0412548147 |
| GSE19899_A1 | Down | -0.6586299730 |
| GSE19899_A2 | Down | -0.5923408824 |
| PubMed_21979375_A1 | Down | -0.4343043631 |
| PubMed_21979375_A2 | Down | -0.2197921870 |
| GSE35957 | Up | 0.1076767397 |
| GSE36640 | Up | 1.4824553501 |
| GSE54402 | Down | -1.3184164729 |
| GSE9593 | Up | 0.1987513309 |
| GSE43922 | Down | -0.2136766336 |
| GSE24585 | Down | -0.1435320766 |
| GSE37065 | Up | 0.2096592891 |
| GSE28863_A1 | Up | 0.4667539916 |
| GSE28863_A2 | Down | -0.4421495626 |
| GSE28863_A3 | Down | -0.3813786192 |
| GSE28863_A4 | Down | -0.0352251709 |
| GSE48662 | Up | 0.2567078150 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-101-3p | MIMAT0000099 | MIRT027280 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
