HCSGD entry for SKOR2

1. General information

Official gene symbolSKOR2
Entrez ID652991
Gene full nameSKI family transcriptional corepressor 2
Other gene symbolsCORL2 FUSSEL18
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIBAbiological_process
GO:0000166Nucleotide bindingIEAmolecular_function
GO:0003714Transcription corepressor activityISSmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedNASbiological_process
GO:0021702Cerebellar Purkinje cell differentiationIEAbiological_process
GO:0021936Regulation of cerebellar granule cell precursor proliferationIEAbiological_process
GO:0030512Negative regulation of transforming growth factor beta receptor signaling pathwayIDAbiological_process
GO:0030514Negative regulation of BMP signaling pathwayIEAbiological_process
GO:0042826Histone deacetylase bindingIEAmolecular_function
GO:0045880Positive regulation of smoothened signaling pathwayIEAbiological_process
GO:0046332SMAD bindingIPImolecular_function
GO:0048814Regulation of dendrite morphogenesisIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81582111240.89992784850.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954--
GSE13712_SHEAR--
GSE13712_STATIC--
GSE19018--
GSE19899_A1--
GSE19899_A2--
PubMed_21979375_A1--
PubMed_21979375_A2--
GSE35957--
GSE36640--
GSE54402--
GSE9593--
GSE43922Up0.1819433894
GSE24585Up0.1096681088
GSE37065Down-0.0599460541
GSE28863_A1Down-0.0317416826
GSE28863_A2Down-0.0889447190
GSE28863_A3Up0.2030596861
GSE28863_A4Down-0.0016638324
GSE48662Down-0.0154954538

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.