HCSGD entry for SLC6A2

1. General information

Official gene symbolSLC6A2
Entrez ID6530
Gene full namesolute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
Other gene symbolsNAT1 NET NET1 SLC6A5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005328Neurotransmitter:sodium symporter activityIEAmolecular_function
GO:0005333Norepinephrine transmembrane transporter activityIEAmolecular_function
GO:0005334Norepinephrine:sodium symporter activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneIEA TAScellular_component
GO:0005887Integral component of plasma membraneIEAcellular_component
GO:0006810TransportTASbiological_process
GO:0006812Cation transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0008504Monoamine transmembrane transporter activityIDAmolecular_function
GO:0009986Cell surfaceIEAcellular_component
GO:0015672Monovalent inorganic cation transportTASbiological_process
GO:0015844Monoamine transportIDAbiological_process
GO:0015874Norepinephrine transportIEAbiological_process
GO:0016020MembraneTAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0030001Metal ion transportTASbiological_process
GO:0034220Ion transmembrane transportTASbiological_process
GO:0035725Sodium ion transmembrane transportTASbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043005Neuron projectionIEAcellular_component
GO:0043014Alpha-tubulin bindingIEAmolecular_function
GO:0045121Membrane raftIEAcellular_component
GO:0048265Response to painIEAbiological_process
GO:0048487Beta-tubulin bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.78373540900.86082111620.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0290071660
GSE13712_SHEARUp0.0382964078
GSE13712_STATICUp0.0116209619
GSE19018Up0.0756816448
GSE19899_A1Up0.0805810828
GSE19899_A2Up0.0470304616
PubMed_21979375_A1Up0.0295453558
PubMed_21979375_A2Down-0.0487621119
GSE35957Up0.0298395553
GSE36640Up0.0635124533
GSE54402Down-0.0074964196
GSE9593Down-0.0388627759
GSE43922Up0.0236841249
GSE24585Down-0.1087159084
GSE37065Up0.0538510898
GSE28863_A1Down-0.0994822837
GSE28863_A2Up0.0070630754
GSE28863_A3Up0.1537197317
GSE28863_A4Up0.1337543074
GSE48662Down-0.0013886145

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.