HCSGD entry for SLC18A2

1. General information

Official gene symbolSLC18A2
Entrez ID6571
Gene full namesolute carrier family 18 (vesicular monoamine), member 2
Other gene symbolsSVAT SVMT VAT2 VMAT2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001975Response to amphetamineIEAbiological_process
GO:0005275Amine transmembrane transporter activityIEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007269Neurotransmitter secretionTASbiological_process
GO:0007568AgingIEAbiological_process
GO:0007626Locomotory behaviorIEAbiological_process
GO:0008144Drug bindingIEAmolecular_function
GO:0008504Monoamine transmembrane transporter activityTASmolecular_function
GO:0009635Response to herbicideIEAbiological_process
GO:0009791Post-embryonic developmentIEAbiological_process
GO:0010043Response to zinc ionIEAbiological_process
GO:0015222Serotonin transmembrane transporter activityIEAmolecular_function
GO:0015844Monoamine transportTASbiological_process
GO:0016020MembraneTAScellular_component
GO:0016265DeathIEAbiological_process
GO:0019899Enzyme bindingIEAmolecular_function
GO:0030073Insulin secretionIEAbiological_process
GO:0030672Synaptic vesicle membraneIEAcellular_component
GO:0031045Dense core granuleIEAcellular_component
GO:0031072Heat shock protein bindingIEAmolecular_function
GO:0032456Endocytic recyclingIEAbiological_process
GO:0035690Cellular response to drugIEAbiological_process
GO:0042220Response to cocaineIEAbiological_process
GO:0042593Glucose homeostasisIEAbiological_process
GO:0042594Response to starvationIEAbiological_process
GO:0043025Neuronal cell bodyIEAcellular_component
GO:0043195Terminal boutonIEAcellular_component
GO:0051412Response to corticosteroneIEAbiological_process
GO:0051589Negative regulation of neurotransmitter transportIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070083Clathrin-sculpted monoamine transport vesicle membraneTAScellular_component
GO:0071242Cellular response to ammonium ionIEAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13711406100.96156530150.74640279161.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0616254663
GSE13712_SHEARUp0.3739367926
GSE13712_STATICUp0.4239337057
GSE19018Up0.1092548324
GSE19899_A1Up0.1948440483
GSE19899_A2Up0.1540778838
PubMed_21979375_A1Up0.9573506844
PubMed_21979375_A2Down-0.2006975913
GSE35957Down-0.1052241661
GSE36640Up0.3962891624
GSE54402Up0.3854758399
GSE9593Down-0.1612192474
GSE43922Up0.0165869780
GSE24585Up0.0412418575
GSE37065Up0.0606578261
GSE28863_A1Down-0.0644488915
GSE28863_A2Down-0.0418794550
GSE28863_A3Up0.2375677351
GSE28863_A4Down-0.0073471845
GSE48662Up0.0966762252

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ReserpineDB00206 APRD00472
AlseroxylonDB00386 APRD00786
EphedraDB01363 -
EphedrineDB01364 -
MMDADB01442 -
3,4-MethylenedioxymethamphetamineDB01454 -
4-MethoxyamphetamineDB01472 EXPT03303
IsomethepteneDB06706 -
PropylhexedrineDB06714 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.