HCSGD entry for SMARCE1


1. General information

Official gene symbolSMARCE1
Entrez ID6605
Gene full nameSWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
Other gene symbolsBAF57
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000228Nuclear chromosomeTAScellular_component
GO:0003677DNA bindingIEAmolecular_function
GO:0003682Chromatin bindingTASmolecular_function
GO:0003713Transcription coactivator activityNASmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0006337Nucleosome disassemblyIDAbiological_process
GO:0006338Chromatin remodelingIDAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterNASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0008080N-acetyltransferase activityIDAmolecular_function
GO:0008152Metabolic processIDAbiological_process
GO:0016514SWI/SNF complexIDA IEAcellular_component
GO:0016922Ligand-dependent nuclear receptor bindingIPImolecular_function
GO:0017053Transcriptional repressor complexIPIcellular_component
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
GO:0071564NpBAF complexIEA ISScellular_component
GO:0071565NBAF complexIEA ISScellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.99007995520.00689598040.99999024730.1653088342

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1100953595
GSE13712_SHEARDown-0.6386357395
GSE13712_STATICDown-0.4646654759
GSE19018Down-0.6722855214
GSE19899_A1Down-0.6469734209
GSE19899_A2Down-0.9170362449
PubMed_21979375_A1Down-0.9984452166
PubMed_21979375_A2Down-1.1079616751
GSE35957Down-0.2459581460
GSE36640Down-0.0889685393
GSE54402Down-0.3275254992
GSE9593Down-0.2566521113
GSE43922Down-0.7498928598
GSE24585Down-0.2541029855
GSE37065Down-0.0615128055
GSE28863_A1Up0.3432649180
GSE28863_A2Down-0.0903796098
GSE28863_A3Down-0.0972113436
GSE28863_A4Up0.2411336865
GSE48662Down-0.2072751863

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020807ProteomicsFunctional MTI (Weak)18668040
hsa-miR-103a-3pMIMAT0000101MIRT027099SequencingFunctional MTI (Weak)20371350
hsa-miR-26b-5pMIMAT0000083MIRT029727MicroarrayFunctional MTI (Weak)19088304
hsa-miR-328-3pMIMAT0000752MIRT043752CLASHFunctional MTI (Weak)23622248
hsa-miR-30c-5pMIMAT0000244MIRT047936CLASHFunctional MTI (Weak)23622248
hsa-miR-1260bMIMAT0015041MIRT052720CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.