HCSGD entry for BNIP2
1. General information
| Official gene symbol | BNIP2 |
|---|---|
| Entrez ID | 663 |
| Gene full name | BCL2/adenovirus E1B 19kDa interacting protein 2 |
| Other gene symbols | BNIP-2 NIP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001824 | Blastocyst development | IEA | biological_process |
| GO:0005096 | GTPase activator activity | TAS | molecular_function |
| GO:0005509 | Calcium ion binding | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005635 | Nuclear envelope | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005814 | Centriole | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006915 | Apoptotic process | IPI | biological_process |
| GO:0031616 | Spindle pole centrosome | IEA | cellular_component |
| GO:0042692 | Muscle cell differentiation | TAS | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | TAS | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0043231 | Intracellular membrane-bounded organelle | IDA | cellular_component |
| GO:0043410 | Positive regulation of MAPK cascade | IEA | biological_process |
| GO:0043547 | Positive regulation of GTPase activity | TAS | biological_process |
| GO:0045666 | Positive regulation of neuron differentiation | IEA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0051057 | Positive regulation of small GTPase mediated signal transduction | IEA | biological_process |
| GO:0051146 | Striated muscle cell differentiation | IEA | biological_process |
| GO:0051149 | Positive regulation of muscle cell differentiation | TAS | biological_process |
| GO:0051297 | Centrosome organization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0767946241 | 0.9178523954 | 0.5857999131 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0888452710 |
| GSE13712_SHEAR | Down | -0.0738731077 |
| GSE13712_STATIC | Down | -0.3294241613 |
| GSE19018 | Up | 0.0351393589 |
| GSE19899_A1 | Up | 0.2271801278 |
| GSE19899_A2 | Up | 0.1298141031 |
| PubMed_21979375_A1 | Down | -0.0971372486 |
| PubMed_21979375_A2 | Up | 0.4965031140 |
| GSE35957 | Up | 0.4786032690 |
| GSE36640 | Up | 0.5011646126 |
| GSE54402 | Up | 0.0821795717 |
| GSE9593 | Up | 0.4161016815 |
| GSE43922 | Down | -0.0504234844 |
| GSE24585 | Up | 0.1497048458 |
| GSE37065 | Up | 0.0919309573 |
| GSE28863_A1 | Up | 0.3927365249 |
| GSE28863_A2 | Up | 0.4905746349 |
| GSE28863_A3 | Down | -0.4638903020 |
| GSE28863_A4 | Up | 0.2306787339 |
| GSE48662 | Down | -0.0357444842 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-20a-5p | MIMAT0000075 | MIRT005481 | qRT-PCR//Western blot | Functional MTI | 21242194 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT005481 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020114 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-132-3p | MIMAT0000426 | MIRT021762 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT027996 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT037172 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
