HCSGD entry for STAC
1. General information
| Official gene symbol | STAC |
|---|---|
| Entrez ID | 6769 |
| Gene full name | SH3 and cysteine rich domain |
| Other gene symbols | STAC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | NAS | cellular_component |
| GO:0007165 | Signal transduction | NAS | biological_process |
| GO:0034605 | Cellular response to heat | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9253631321 | 0.0085854755 | 0.9999902473 | 0.1849068627 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0024382843 |
| GSE13712_SHEAR | Down | -0.4308076845 |
| GSE13712_STATIC | Down | -0.2709472793 |
| GSE19018 | Down | -0.2253909754 |
| GSE19899_A1 | Up | 0.2322150801 |
| GSE19899_A2 | Down | -0.0688989648 |
| PubMed_21979375_A1 | Down | -0.1851197045 |
| PubMed_21979375_A2 | Down | -0.3322776868 |
| GSE35957 | Up | 0.3563923301 |
| GSE36640 | Down | -0.1605889309 |
| GSE54402 | Down | -0.0124775849 |
| GSE9593 | Up | 0.3268163310 |
| GSE43922 | Up | 0.0169711480 |
| GSE24585 | Down | -0.9320813314 |
| GSE37065 | Down | -0.7583772548 |
| GSE28863_A1 | Down | -0.6589605006 |
| GSE28863_A2 | Down | -0.8210609712 |
| GSE28863_A3 | Down | -0.0156309632 |
| GSE28863_A4 | Down | -0.4294695833 |
| GSE48662 | Up | 0.0821930379 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 15574883 | In addition to DUSP1 and known p53 and E2F targets, a number of genes such as PHLDA1, NR4A3, and a novel splice variant of STAC were implicated in senescence |
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