HCSGD entry for SUPT4H1

1. General information

Official gene symbolSUPT4H1
Entrez ID6827
Gene full namesuppressor of Ty 4 homolog 1 (S. cerevisiae)
Other gene symbolsSPT4 SPT4H SUPT4H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDA IEAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0006338Chromatin remodelingTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006355Regulation of transcription, DNA-templatedTASbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterTASbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterIDA TASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0032044DSIF complexIDAcellular_component
GO:0032785Negative regulation of DNA-templated transcription, elongationIDAbiological_process
GO:0032786Positive regulation of DNA-templated transcription, elongationIDA IEAbiological_process
GO:0034244Negative regulation of transcription elongation from RNA polymerase II promoterIEAbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0050434Positive regulation of viral transcriptionTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.12637879260.62493187570.72455155741.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4354290049
GSE13712_SHEARUp0.4374142755
GSE13712_STATICUp0.4408264588
GSE19018Down-0.1175353441
GSE19899_A1Down-0.0963931367
GSE19899_A2Up0.1922761386
PubMed_21979375_A1Up0.4377038785
PubMed_21979375_A2Down-0.0813966431
GSE35957Up0.1270385905
GSE36640Down-0.1914894268
GSE54402Up0.0754797390
GSE9593Up0.0470976031
GSE43922Up0.0378390619
GSE24585Up0.5059620162
GSE37065Up0.0428231943
GSE28863_A1Down-0.4675134584
GSE28863_A2Down-0.4385020533
GSE28863_A3Down-0.3152335005
GSE28863_A4Up0.4011218581
GSE48662Up0.1359862538

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-7-5pMIMAT0000252MIRT025924MicroarrayFunctional MTI (Weak)19073608
hsa-miR-96-5pMIMAT0000095MIRT027878SequencingFunctional MTI (Weak)20371350
hsa-let-7e-5pMIMAT0000066MIRT051537CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.