HCSGD entry for BST2

1. General information

Official gene symbolBST2
Entrez ID684
Gene full namebone marrow stromal cell antigen 2
Other gene symbolsCD317 TETHERIN
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002737Negative regulation of plasmacytoid dendritic cell cytokine productionIDAbiological_process
GO:0004871Signal transducer activityIMPmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005770Late endosomeIEAcellular_component
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006959Humoral immune responseTASbiological_process
GO:0007165Signal transductionIMPbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008191Metalloendopeptidase inhibitor activityIDAmolecular_function
GO:0008283Cell proliferationTASbiological_process
GO:0009615Response to virusIDAbiological_process
GO:0009986Cell surfaceISScellular_component
GO:0010466Negative regulation of peptidase activityIDAbiological_process
GO:0010951Negative regulation of endopeptidase activityIDAbiological_process
GO:0016324Apical plasma membraneISScellular_component
GO:0030308Negative regulation of cell growthIDAbiological_process
GO:0030336Negative regulation of cell migrationIDAbiological_process
GO:0031225Anchored component of membraneIEAcellular_component
GO:0032956Regulation of actin cytoskeleton organizationISSbiological_process
GO:0034341Response to interferon-gammaISSbiological_process
GO:0035455Response to interferon-alphaISSbiological_process
GO:0035456Response to interferon-betaISSbiological_process
GO:0042113B cell activationIEAbiological_process
GO:0042803Protein homodimerization activityIPImolecular_function
GO:0043086Negative regulation of catalytic activityIDAbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIMPbiological_process
GO:0045071Negative regulation of viral genome replicationIDAbiological_process
GO:0045087Innate immune responseIDAbiological_process
GO:0045121Membrane raftIEAcellular_component
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0051607Defense response to virusIDAbiological_process
GO:0052547Regulation of peptidase activityIDAbiological_process
GO:0052548Regulation of endopeptidase activityIDAbiological_process
GO:1901253Negative regulation of intracellular transport of viral materialIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00687750090.27254817070.21627562720.9987342329

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.3838036232
GSE13712_SHEARUp0.9740021983
GSE13712_STATICUp1.1721508530
GSE19018Up0.1382145947
GSE19899_A1Up0.0031388854
GSE19899_A2Up0.1174257394
PubMed_21979375_A1Up0.0530407843
PubMed_21979375_A2Down-0.1514125421
GSE35957Down-4.3564196430
GSE36640Up0.7041010321
GSE54402Down-0.1427526073
GSE9593Up0.3582638126
GSE43922Up0.0113509018
GSE24585Up2.2877193827
GSE37065Up0.8345571446
GSE28863_A1Down-0.2642615226
GSE28863_A2Down-0.1785482409
GSE28863_A3Up0.4949172001
GSE28863_A4Up0.0808701096
GSE48662Up0.1874664340

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.