HCSGD entry for TCN2
1. General information
| Official gene symbol | TCN2 |
|---|---|
| Entrez ID | 6948 |
| Gene full name | transcobalamin II |
| Other gene symbols | D22S676 D22S750 II TC TC II TC-2 TC2 TCII |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | TAS | cellular_component |
| GO:0005768 | Endosome | TAS | cellular_component |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006824 | Cobalt ion transport | IEA | biological_process |
| GO:0009235 | Cobalamin metabolic process | IBA TAS | biological_process |
| GO:0015889 | Cobalamin transport | IEA | biological_process |
| GO:0031419 | Cobalamin binding | IBA IDA IEA | molecular_function |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2387272634 | 0.1431986323 | 0.9245939229 | 0.7288879157 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1801620237 |
| GSE13712_SHEAR | Down | -1.6938063547 |
| GSE13712_STATIC | Down | -1.1040050908 |
| GSE19018 | Up | 0.0997259742 |
| GSE19899_A1 | Down | -0.0843848978 |
| GSE19899_A2 | Down | -0.1522097355 |
| PubMed_21979375_A1 | Down | -0.4416055252 |
| PubMed_21979375_A2 | Down | -0.2991556604 |
| GSE35957 | Up | 0.0346703698 |
| GSE36640 | Up | 0.2055208317 |
| GSE54402 | Down | -0.0152430255 |
| GSE9593 | Up | 0.1766191893 |
| GSE43922 | Down | -0.2344012016 |
| GSE24585 | Up | 0.6083629508 |
| GSE37065 | Up | 0.4712235912 |
| GSE28863_A1 | Up | 0.2162234067 |
| GSE28863_A2 | Up | 0.7314848131 |
| GSE28863_A3 | Up | 0.1010735239 |
| GSE28863_A4 | Up | 0.3037942060 |
| GSE48662 | Up | 0.2798352440 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
