HCSGD entry for TMBIM6


1. General information

Official gene symbolTMBIM6
Entrez ID7009
Gene full nametransmembrane BAX inhibitor motif containing 6
Other gene symbolsBAXI1 BI-1 TEGT
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusTAScellular_component
GO:0005783Endoplasmic reticulumTAScellular_component
GO:0005789Endoplasmic reticulum membraneIEAcellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0006986Response to unfolded proteinIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0032469Endoplasmic reticulum calcium ion homeostasisIEAbiological_process
GO:0043066Negative regulation of apoptotic processIEAbiological_process
GO:0070059Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03357405110.99038698380.42148750601.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4088963482
GSE13712_SHEARUp0.1049056190
GSE13712_STATICUp0.0389031389
GSE19018Up0.4899669644
GSE19899_A1Up0.4666054719
GSE19899_A2Up0.5366803032
PubMed_21979375_A1Up0.3043438908
PubMed_21979375_A2Up0.3952555479
GSE35957Down-0.1988315944
GSE36640Up0.2118288618
GSE54402Up0.0207287715
GSE9593Up0.1974163844
GSE43922Up0.2825568817
GSE24585Up0.2023328294
GSE37065Up0.0387233979
GSE28863_A1Up0.1956899193
GSE28863_A2Up0.1905179044
GSE28863_A3Down-0.2468739480
GSE28863_A4Up0.1221077980
GSE48662Up0.0398648455

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-155-5pMIMAT0000646MIRT020530ProteomicsFunctional MTI (Weak)18668040
hsa-miR-16-5pMIMAT0000069MIRT031401ProteomicsFunctional MTI (Weak)18668040
hsa-miR-484MIMAT0002174MIRT042252CLASHFunctional MTI (Weak)23622248
hsa-miR-186-5pMIMAT0000456MIRT045127CLASHFunctional MTI (Weak)23622248
hsa-miR-19b-3pMIMAT0000074MIRT050638CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.