HCSGD entry for TIAL1
1. General information
| Official gene symbol | TIAL1 |
|---|---|
| Entrez ID | 7073 |
| Gene full name | TIA1 cytotoxic granule-associated RNA binding protein-like 1 |
| Other gene symbols | TCBP TIAR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0005634 | Nucleus | ISS | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0006357 | Regulation of transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0006952 | Defense response | TAS | biological_process |
| GO:0007281 | Germ cell development | IEA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0010494 | Cytoplasmic stress granule | ISS | cellular_component |
| GO:0017091 | AU-rich element binding | IEA | molecular_function |
| GO:0017145 | Stem cell division | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9577327951 | 0.1490928536 | 0.9999902473 | 0.7466993151 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0069112772 |
| GSE13712_SHEAR | Down | -0.0715087536 |
| GSE13712_STATIC | Down | -0.1507102316 |
| GSE19018 | Down | -0.1541997190 |
| GSE19899_A1 | Down | -0.2813215870 |
| GSE19899_A2 | Down | -0.3586314897 |
| PubMed_21979375_A1 | Up | 0.1923058979 |
| PubMed_21979375_A2 | Down | -0.2230723283 |
| GSE35957 | Up | 0.0973146835 |
| GSE36640 | Down | -0.1551282411 |
| GSE54402 | Down | -0.0924263598 |
| GSE9593 | Down | -0.1276694963 |
| GSE43922 | Up | 0.0217494797 |
| GSE24585 | Up | 0.0024032725 |
| GSE37065 | Down | -0.3063172189 |
| GSE28863_A1 | Up | 0.1705581312 |
| GSE28863_A2 | Up | 0.1223541893 |
| GSE28863_A3 | Down | -0.4032078060 |
| GSE28863_A4 | Up | 0.2174176638 |
| GSE48662 | Down | -0.4389077693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025099 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028531 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-27a-3p | MIMAT0000084 | MIRT028690 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-181c-5p | MIMAT0000258 | MIRT047221 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
