HCSGD entry for TPM2


1. General information

Official gene symbolTPM2
Entrez ID7169
Gene full nametropomyosin 2 (beta)
Other gene symbolsAMCD1 DA1 DA2B NEM4 TMSB
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003779Actin bindingIDAmolecular_function
GO:0005829CytosolTAScellular_component
GO:0005862Muscle thin filament tropomyosinTAScellular_component
GO:0006936Muscle contractionTASbiological_process
GO:0008307Structural constituent of muscleTASmolecular_function
GO:0030049Muscle filament slidingTASbiological_process
GO:0043462Regulation of ATPase activityIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.66663240380.02330537590.99999024730.2942066187

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.2768804020
GSE13712_SHEARUp0.0857688214
GSE13712_STATICDown-0.0626319523
GSE19018Down-0.4229531684
GSE19899_A1Down-0.2366705308
GSE19899_A2Down-0.0725434111
PubMed_21979375_A1Down-0.5814959782
PubMed_21979375_A2Down-0.1571076731
GSE35957Up0.1534445279
GSE36640Up0.5838360213
GSE54402Down-0.2666196808
GSE9593Down-0.2276924433
GSE43922Down-0.3062093555
GSE24585Up0.3580924461
GSE37065Down-0.4618580710
GSE28863_A1Down-0.3755619773
GSE28863_A2Down-0.8995410079
GSE28863_A3Up0.6158080953
GSE28863_A4Up0.2675592258
GSE48662Down-0.4457247232

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT001326pSILAC//ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1MIMAT0000416MIRT001326Proteomics;MicroarrayFunctional MTI (Weak)18668037
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.